This special issue features a collection of reviews on the endoplasmic reticulum (ER), dysfunction of which has been implicated in multiple major human diseases, including diabetes and neurodegenerative diseases. These reviews provide unique insights into the physiological role of, and the mechanisms behind, the endoplasmic reticulum stress response, as well as possible targets for the treatment of human diseases involving ER stress.
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I have always been fascinated with the endoplasmic reticulum, and scientists are finding out that problems in that part of cells can cause disease.
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