Wednesday, Jul 16 (Psych Central) --
A new study suggests variations in the serotonin transporter gene could explain why some people with depression respond better than others to treatment with citalopram (Celexa), an antidepressant medication.
Researchers examined the serotonin transporter gene, or SLC6A4, in 1,914 study participants. The study showed that two variations in this gene have a direct bearing on how individuals might respond to citalopram. SLC6A4 produces a protein that plays an important role in achieving an antidepressant response.
Pharmacogenetics, the study of how people’s genetic makeup affects their response to medications, could improve patient outcomes by matching patients with the right drug from the start rather than endure the arduous process of trial and error.
clipped from psychcentral.com
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